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WebMay 27, 2012 · PNS stimulants are supposed to cause vasoconstriction so they can relieve nasal congestion, they're supposed to raise HR and BP, they're supposed to cause more … WebJan 2, 2024 · Phenylephrine is very poorly absorbed from the GI tract, but when used topically, is an extremely potent vasoconstrictor. Topical decongestants often give amazing initial results. Congestion can clear within a matter of seconds, and the effects of the sprays can last up to 12 hours. As mentioned, however, they have significant drawbacks. diablo 2 resurrected thawing potion
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